De colaboração com os Drs. J. Lima , A. Cardoso e os Profs. Doutores R. Branco e N. Canha
(EUROPEAN JOURNAL OF LYMPHOLOGY AND RELATED PROBLEMS 1-2; 33-36, 1990).
The twenty-four hours articular retention and nodal accumulation of 99mTc labelled dextran (Molecular weight = 70000) injected in the articular cavity of normal and pathological knees have been studied by scintigraphic techniques in 115 consecutive patients suffering from early or advanced chondropathy or from ostheoarthritis. As regards the injected activity, the pathological joints exhibited higher retention (decreased lymphatic elimination) of the label in the articulation than the normal joints. On the other hand, the nodal accumulation of the labelled molecules appeared greater in the pathological joints than in the normal ones. The present study thus demonstrates the existence of abnormal lymphatic function corresponding to the severity of the disease.
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